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Signal Inhibitors and Activators
VX-702
$211.2/ 25mg1 PHYSICAL AND CHEMICAL PROPERTIES
QuantityTotal: $211
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Product Information
Kinase Inhibitor Name VX-702
Formula C19H12F4N4O2
Solubility DMSO
Purity 98%
CAS No. 479543-46-9
M.W. 404.3
Storage/Stability at -20℃ 2 years
Price211.2$
Research AreaStem Cells Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction
![activation of p38 MAPKs leads to gene transcription and translation, followed by an increase of inflammatory mediators, such as TNFα, IL-1β, cyclooxygenase (COX)-2, IL-6, IL-12 all of which have been demonstrated to play important roles in autoimmune diseases arthritis (RA) and/or cardiovascular diseases. In an ex vivo blood assay primed with dose-dependently inhibited the production of IL-6, IL-1β and TNFα (IC50 = 59, 122 and 99 [3] To determine the effects, if any, of VX-702 on platelet function alone, or in conjunction](/img/pdfimg/E1KS6005/E1KS6005-001.jpg)
activation of p38 MAPKs leads to gene transcription and translation, followed by an increase of inflammatory mediators, such as TNFα, IL-1β, cyclooxygenase (COX)-2, IL-6, IL-12 all of which have been demonstrated to play important roles in autoimmune diseases arthritis (RA) and/or cardiovascular diseases. In an ex vivo blood assay primed with dose-dependently inhibited the production of IL-6, IL-1β and TNFα (IC50 = 59, 122 and 99 [3] To determine the effects, if any, of VX-702 on platelet function alone, or in conjunction
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