BAY 11-7082NF-κB Inhibitor
Datasheet

Catalog Number:
E1B1523
Amount:
Form of Antibody:
BAY 11-7082(E)-3-[(4-methylphenylsulfonyl]-2-propenenitrile
CAS NO: 195462-67-7
PHYSICAL APPEARANCE: Off-white solid (m.p. 128-130°C)
MOLECULAR FORMULA: C10H9NO2S
Molecular Weight:
207.3
Purity:
99%
Storage/Stability:
Store solutions at -20°C for up to 1 year.
Recommended Dilutions:
Inhibitor of cytokine-induced NF-κB phosphorylation. Inhibited NF-κB activated expression of ICAM-1, VCAM-1, E-selectin, IL-6 and IL-8, in TNF treated HUVECs, with IC50’s of 5-10 μM. The inhibition of NF-κB phosphorylation and cell adhesion molecule expression and the stabilization of NF-κB were found to be irreversible effects.
References:
J.W. Pierce et al. J. Biol. Chem. 1997 272 21096
The pharmacological and toxicological properties of this product have not been fully investigated. Exercise caution in use and handling. This product must not be used in humans.
Price:
60$

BAY 11-7082NF-κB InhibitorDatasheet