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Product Information
Kinase Inhibitor Name PTC124 (Ataluren)
M.W. 284.24 Formula: C15H9FN2O3 Solubility: DMSO Purity: >99% Storage: at -20℃ 2 years CAS No.: 775304-57-9
Price225.6$
Research AreaStem Cells Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction
(Ataluren) targets genetic disorders caused by nonsense mutations. [1] PTC124 compound that promotes of the human CFTR-G542X nonsense allele in a CF of PTC124 treatment of cystic fibrosis caused by nonsense mutations: a induces dose-dependent suppression of premature translational termination on normal termination or mRNA decay. [1]In safety pharmacology studies