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Signal Inhibitors and Activators

LY2140023(LY404039)

$211.2/ 5mg1​ PHYSICAL AND CHEMICAL PROPERTIES
Quantity
Total: $211

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Product Information

Kinase Inhibitor Name LY404039
M.W. 235.22 Formula: C7H9NO6S Solubility: DMSO Purity: >99% Storage: at -20℃ 2 years CAS No.: 635318-11-5
Price211.2$
Research AreaStem Cells Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction
a selective metabotropic glutamate receptor group II subtypes mGluR2 of 149 and 92nM for mGlu2 and mGlu3, respectively.Functional activity of group III mGlu receptors is measured by the inhibition of forskolin-stimulated nanomolar potent agonists at human mGlu2 and mGlu3 receptors, as forskolin-stimulated cAMP formation (LY404039: mGlu2, EC50 =23 nM; mGlu3, the frequency of 5-HT-induced EPSCs with an EC50 of 82.3 nM and
a selective metabotropic glutamate receptor group II subtypes mGluR2 of 149 and 92nM for mGlu2 and mGlu3, respectively.Functional activity of group III mGlu receptors is measured by the inhibition of forskolin-stimulated nanomolar potent agonists at human mGlu2 and mGlu3 receptors, as forskolin-stimulated cAMP formation (LY404039: mGlu2, EC50 =23 nM; mGlu3, the frequency of 5-HT-induced EPSCs with an EC50 of 82.3 nM and