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Signal Inhibitors and Activators

ADX-47273

$633.6/ 5mg1​ PHYSICAL AND CHEMICAL PROPERTIES
Quantity
Total: $634

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Product Information

Kinase Inhibitor Name ADX-47273
FormulaC20H17F2N3O2
SolubilityDMSO ≥74 mg/mL   Water <1 mg/mL   Ethanol ≥27 mg/mL
Stability:
2 years       -20℃     Powder
1 week        -4℃     in DMSO
1 month     -80℃     in DMSO
CAS No.851881-60-2
M.W.369.36
Price633.5999999999999$
Research AreaStem Cells Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction
novel, potent and selective metabotropic glutamate receptor 5 nM in human embryonic kidney 293 cells expressing rat mGlu5. glutamate response curve to the left (9-fold at 1 μM) and competed (phenylethynyl) pyridine with a Ki of 4.3 μM in a dose-dependent vivo, ADX-47273 elevated extracellular signal-regulated element-binding protein phosphorylation in hippocampus and
novel, potent and selective metabotropic glutamate receptor 5 nM in human embryonic kidney 293 cells expressing rat mGlu5. glutamate response curve to the left (9-fold at 1 μM) and competed (phenylethynyl) pyridine with a Ki of 4.3 μM in a dose-dependent vivo, ADX-47273 elevated extracellular signal-regulated element-binding protein phosphorylation in hippocampus and