
novel, potent and selective metabotropic glutamate receptor 5 nM in human embryonic kidney 293 cells expressing rat mGlu5. glutamate response curve to the left (9-fold at 1 μM) and competed (phenylethynyl) pyridine with a Ki of 4.3 μM in a dose-dependent vivo, ADX-47273 elevated extracellular signal-regulated element-binding protein phosphorylation in hippocampus and