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Signal Inhibitors and Activators
WAY-600
$816/ 5mg1 PHYSICAL AND CHEMICAL PROPERTIES
QuantityTotal: $816
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Product Information
Kinase Inhibitor Name WAY-600
FormulaC28H30N8O
SolubilityDMSO ≥17 mg/mL Water <1 mg/mL Ethanol ≥2 mg/mL
Stability:
2 years -20℃ Powder
1 week -4℃ in DMSO
1 month -80℃ in DMSO
Stability:
2 years -20℃ Powder
1 week -4℃ in DMSO
1 month -80℃ in DMSO
CAS No.1062159-35-6
M.W.494.59
Price816$
Research AreaStem Cells Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction
potent ATP-competitive mTOR inhibitor with an IC50 of about 9 nM. It target of rapamycin (mTOR) is centrally involved in cell growth, has significant selectivity against mTOR over phosphatidylinositol (>100-fold). WAY-600 treated HEK293 cells indicated a 50% inhibition of with the 11% suppression by rapamycin. Unlike the rapalogs,WAY-600 mTORC2-dependent phosphorylation of AKT in vitro and in vivo. In
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