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Signal Inhibitors and Activators
R547
$1420.8/ 2mg1 PHYSICAL AND CHEMICAL PROPERTIES
QuantityTotal: $1421
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Product Information
Kinase Inhibitor Name R547
FormulaC18H21F2N5O4S
SolubilityStability:
2 years -20℃ Powder
1 week -4℃ in DMSO
1 month -80℃ in DMSO
2 years -20℃ Powder
1 week -4℃ in DMSO
1 month -80℃ in DMSO
CAS No.741713-40-6
M.W.441.45
Price1420.8$
Research AreaStem Cells Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction
selective inhibitor of cell cycle and transcriptional cyclin dependent kinases for CDK1/cyclin B, CDK2/cyclin E, and CDK4/cyclin D1. In vivo, R547 showed kinase inhibition profile and the preclinical antitumor activity of R547 for development for use in the treatment of solid tumors. The cyclin-dependent regulators of cell cycle progression. Aberrant expression or altered activity kinase (CDK) complexes leads to escape of cells from cell cycle control,
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