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Signal Inhibitors and Activators
NVP-BSK805
$816/ 5mg1 PHYSICAL AND CHEMICAL PROPERTIES
QuantityTotal: $816
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Product Information
Kinase Inhibitor Name NVP-BSK805
FormulaC27H28F2N6O.2HCl
SolubilityDMSO ≥113 mg/mL Water ≥8 mg/mL Ethanol ≥17 mg/mL
Stability:
2 years -20℃ Powder
1 week -4℃ in DMSO
1 month -80℃ in DMSO
Stability:
2 years -20℃ Powder
1 week -4℃ in DMSO
1 month -80℃ in DMSO
CAS No.1092499-93-8
M.W.563.47
Price816$
Research AreaStem Cells Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction
dihydrochloride is a potent and selective quinoxaline JAK2 inhibitor with nM for JAK2 JH1, FL JAK V617F and FL JAK2 wt, respectively. displays more than 20-fold selectivity over the other JAK family members over a panel of kinases in vitro. NVP-BSK805 has less inhibitory activity JAK3 JH1 (IC50=18.7 nM). In proliferation assays with most of Ba/F3-based dihydrochloride blocks the growth of JAKV617F cells and induces
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