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Signal Inhibitors and Activators
KW-2478
$816/ 5mg1 PHYSICAL AND CHEMICAL PROPERTIES
QuantityTotal: $816
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Product Information
Kinase Inhibitor Name KW-2478
FormulaC30H42N2O9.HCl
SolubilityStability:
2 years -20℃ Powder
1 week -4℃ in DMSO
1 month -80℃ in DMSO
2 years -20℃ Powder
1 week -4℃ in DMSO
1 month -80℃ in DMSO
CAS No.819812-18-5
M.W.611.12
Price816$
Research AreaStem Cells Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction
a novel non-ansamycin potent Hsp90 inhibitor with an IC50 of 3.8 nM. analogue antagonist for Hsp90. KW-2478 suppressed the binding of bRD to manner. KW-2478 indicated a potent anti-cancer activity both in clearly prevented cancer cell growth in all cell lines, with EC50 of 101-252, B-cell lymphoma, mantle cell lymphoma and multiple myeloma, respectively. growth inhibitory activity in primary CLL (n=3) and NHL (n=2) cells with
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