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Signal Inhibitors and Activators
CHIR-124
$211.2/ 2mg1 PHYSICAL AND CHEMICAL PROPERTIES
QuantityTotal: $211
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Product Information
Kinase Inhibitor Name CHIR-124
FormulaC23H22ClN5O
SolubilityStability:
2 years -20℃ Powder
1 week -4℃ in DMSO
1 month -80℃ in DMSO
2 years -20℃ Powder
1 week -4℃ in DMSO
1 month -80℃ in DMSO
CAS No.405168-58-3
M.W.419.91
Price211.2$
Research AreaStem Cells Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction
novel and potent chk1 inhibitor with an IC50 of 0.3 nM. Chk1 kinase S and G2/M phase cell cycle checkpoints in response to DNA damage. of chk1 can selectively sensitize tumor cells with mutant p53 to quinolone-based small molecule that is structurally unrelated to other known interacts synergistically with camptothecin in causing growth inhibition in by isobologram analysis. In HCT116 human colon carcinoma
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