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Signal Inhibitors and Activators
CAY10505
$151.2/ 10mg1 PHYSICAL AND CHEMICAL PROPERTIES
QuantityTotal: $151
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Product Information
Kinase Inhibitor Name CAY10505
FormulaC14H8FNO3S
SolubilityDMSO ≥58 mg/mL Water <1 mg/mL Ethanol <1 mg/mL
Stability:
2 years -20℃ Powder
1 week -4℃ in DMSO
1 month -80℃ in DMSO
Stability:
2 years -20℃ Powder
1 week -4℃ in DMSO
1 month -80℃ in DMSO
CAS No.1218777-13-9
M.W.289.28
Price151.2$
Research AreaStem Cells Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction
potent PI3Kγ inhibitor with an IC50 of 30 nM. Phosphoinositide 3-kinase in hematopoietic cells and plays several important roles in immunity. α, β, and δ isoforms with IC50 of 0.94, 20, and 20 μM, respectively. only the unrelated casein kinase 2 (CK2, IC50 = 20 nM). CAY10505 of the PI3K substrate PKB/Akt in murine macrophages (IC50 = CAY10505 decreases neutrophil recruitment in mice to an extent that is
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