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Signal Inhibitors and Activators

GSK1120212 (JTP-74057)

E1KS2673DatasheetCOAMSDS
$362.4/ 5mg1​ PHYSICAL AND CHEMICAL PROPERTIES
Quantity
Total: $362

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Product Information

Kinase Inhibitor Name GSK1120212 (JTP-74057)
FormulaC26H23FIN5O4
SolubilityDMSO ≥6 mg/mL   Water <1 mg/mL   Ethanol <1 mg/mL
Stability:
2 years       -20℃     Powder
1 week        -4℃     in DMSO
1 month     -80℃     in DMSO
CAS No.871700-17-3
M.W.615.39
Price362.4$
Research AreaStem Cells Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction
(JTP-74057) is a reversible, selective, allosteric MEK1/MEK2 kinase nM for MEK1 and MEK2. [1] GSK1120212 (JTP-74057) MEK2 kinases rather than activities of other 98 kinases. it led to the growth inhibition and upregulate p15INK4b cancer cell lines tested. In nude animal mice studies, JTP-74057 COLO205 xenografts when GSK1120212 (JTP-74057) was daily
(JTP-74057) is a reversible, selective, allosteric MEK1/MEK2 kinase nM for MEK1 and MEK2. [1] GSK1120212 (JTP-74057) MEK2 kinases rather than activities of other 98 kinases. it led to the growth inhibition and upregulate p15INK4b cancer cell lines tested. In nude animal mice studies, JTP-74057 COLO205 xenografts when GSK1120212 (JTP-74057) was daily
📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

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