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Signal Inhibitors and Activators

WYE-687

$816/ 5mg1​ PHYSICAL AND CHEMICAL PROPERTIES
Quantity
Total: $816

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Product Information

Kinase Inhibitor Name WYE-687
FormulaC28H32N8O3
SolubilityDMSO ≥1 mg/mL   Water <1 mg/mL   Ethanol <1 mg/mL
Stability:
2 years       -20℃     Powder
1 week        -4℃     in DMSO
1 month     -80℃     in DMSO
CAS No.1062161-90-3
M.W.528.61
Price816$
Research AreaStem Cells Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction
potent ATP-competitive mTOR inhibitor with an IC50 of 7 nM. It is well target of rapamycin (mTOR) is centrally involved in cell growth, Significantly, the pyrazolopyrimidines were selective for mTOR over PI3Kα were poorly active in a panel of 24 protein kinases. Unlike the mTORC2-dependent phosphorylation of AKT in vitro and in vivo. In various the mTORC1 substrate P-S6K(T389) and mTORC2 substrate
potent ATP-competitive mTOR inhibitor with an IC50 of 7 nM. It is well target of rapamycin (mTOR) is centrally involved in cell growth, Significantly, the pyrazolopyrimidines were selective for mTOR over PI3Kα were poorly active in a panel of 24 protein kinases. Unlike the mTORC2-dependent phosphorylation of AKT in vitro and in vivo. In various the mTORC1 substrate P-S6K(T389) and mTORC2 substrate