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Signal Inhibitors and Activators

WYE-125132

$816/ 5mg1​ PHYSICAL AND CHEMICAL PROPERTIES
Quantity
Total: $816

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Product Information

Kinase Inhibitor Name WYE-125132
FormulaC27H33N7O4
SolubilityDMSO ≥104 mg/mL   Water <1 mg/mL   Ethanol <1 mg/mL
Stability:
2 years       -20℃     Powder
1 week        -4℃     in DMSO
1 month     -80℃     in DMSO
CAS No.1144068-46-1
M.W.519.6
Price816$
Research AreaStem Cells Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction
highly potent, ATP-competitive and specific mTOR kinase inhibitor blocked the activity of the both of mTORC1 and mTORC2 in in vivo. WYE-125132 is 5,000-fold more selective than blocked amino acid-induced phosphorylation of Maf1, of mTOR. WYE-132-treated MG63 markedly upregulated the showed a substantially more effective inhibition in many
highly potent, ATP-competitive and specific mTOR kinase inhibitor blocked the activity of the both of mTORC1 and mTORC2 in in vivo. WYE-125132 is 5,000-fold more selective than blocked amino acid-induced phosphorylation of Maf1, of mTOR. WYE-132-treated MG63 markedly upregulated the showed a substantially more effective inhibition in many