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Signal Inhibitors and Activators
NPS-2143
$362.4/ 10mg1 PHYSICAL AND CHEMICAL PROPERTIES
QuantityTotal: $362
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Product Information
Kinase Inhibitor Name NPS-2143
FormulaC24H25ClN2O2
SolubilityDMSO ≥82 mg/mL Water <1 mg/mL Ethanol <1 mg/mL
Stability:
2 years -20℃ Powder
1 week -4℃ in DMSO
1 month -80℃ in DMSO
Stability:
2 years -20℃ Powder
1 week -4℃ in DMSO
1 month -80℃ in DMSO
CAS No.284035-33-2
M.W.408.92
Price362.4$
Research AreaStem Cells Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction
is a selective potent calcium ion-sensing receptor antagonist with IC50 of 43 and Ca2+ concentrations and parathyroid hormone secretion, respectively. NPS-2143 in cytoplasmic Ca2+ concentrations elicited by human Ca2+ receptors expressed in 2143 , even at much higher concentrations (3 μM), did not influence the activity of a number protein-coupled receptors, including those most structurally homologous to the Ca2+
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