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Signal Inhibitors and Activators
GW3965
$292.8/ 5mg1 PHYSICAL AND CHEMICAL PROPERTIES
QuantityTotal: $293
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Product Information
Kinase Inhibitor Name GW3965 HCl
FormulaC33H31ClF3NO3.HCl
SolubilityDMSO ≥124 mg/mL Water <1 mg/mL Ethanol ≥7 mg/mL
Stability:
2 years -20℃ Powder
1 week -4℃ in DMSO
1 month -80℃ in DMSO
Stability:
2 years -20℃ Powder
1 week -4℃ in DMSO
1 month -80℃ in DMSO
CAS No.405911-17-3
M.W.618.51
Price292.8$
Research AreaStem Cells Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction
is a synthetic selective, active non-steroidal liver X receptor (LXR) agonist μM for hLXRα and hLXRβ, respectively. Angiotensin II-mediated increases reduced by GW3965 HCl . In HepG2 cells, the EC50 for GW3965 is greater GW3965 HCl decreased lesion area by 53% 34% in male and female induced expression of ATP-binding cassettes A1 and G1 in modified macrophages in vitro as well as in the aortas of hyperlipidemic mice.
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