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Signal Inhibitors and Activators

PNU-120596

$261.6/ 10mg1​ PHYSICAL AND CHEMICAL PROPERTIES
Quantity
Total: $262

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Product Information

Kinase Inhibitor Name PNU-120596
FormulaC13H14ClN3O4
SolubilityDMSO ≥62 mg/mL   Water <1 mg/mL   Ethanol ≥1 mg/mL
Stability:
2 years       -20℃     Powder
1 week        -4℃     in DMSO
1 month     -80℃     in DMSO
CAS No.501925-31-1
M.W.311.72
Price261.6$
Research AreaStem Cells Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction
a potent and selective positive allosteric α7 neuronal nicotinic with an EC50 of 0.2 μM. PNU-120596 has no detectable effect on Discovered in a high-throughput screen, PNU-120596 enhanced by an engineered variant of the human α7 nAChR. Electrophysiology PNU-120596 increased peak agonist-evoked currents mediated proved a pronounced prolongation of the triggered response in
a potent and selective positive allosteric α7 neuronal nicotinic with an EC50 of 0.2 μM. PNU-120596 has no detectable effect on Discovered in a high-throughput screen, PNU-120596 enhanced by an engineered variant of the human α7 nAChR. Electrophysiology PNU-120596 increased peak agonist-evoked currents mediated proved a pronounced prolongation of the triggered response in