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Signal Inhibitors and Activators
MG-132
$151.2/ 5mg1 PHYSICAL AND CHEMICAL PROPERTIES
QuantityTotal: $151
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Product Information
Kinase Inhibitor Name MG-132
FormulaC26H41N3O5
SolubilityDMSO ≥95 mg/mL Water <1 mg/mL Ethanol ≥95 mg/mL
Stability:
2 years -20℃ Powder
1 week -4℃ in DMSO
1 month -80℃ in DMSO
Stability:
2 years -20℃ Powder
1 week -4℃ in DMSO
1 month -80℃ in DMSO
CAS No.133407-82-6
M.W.475.62
Price151.2$
Research AreaStem Cells Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction
a potent cell-permeable proteasome and calpain inhibitor with IC50 of 0.1 and proteasome and calpain, respectively. The Ki of MG132 is 4 nM. MG132 NF-κB activation and IκBα degradation with an IC50 of 3 µM and prevents induces neurite outgrowth in PC12 cells and has anticancer properties the degradation of ubiquitin-conjugated proteins in mammalian cells and by the 26S complex without affecting its ATPase or isopeptidase activities.
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