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Signal Inhibitors and Activators
Rosiglitazone maleate
$211.2/ 25mg
QuantityTotal: $211
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Product Information
Kinase Inhibitor Name S Rosiglitazone maleate
FormulaC18H19N3O3S.C4H4O4
SolubilityDMSO ≥95 mg/mL Water <1 mg/mL Ethanol ≥6 mg/mL
Stability:
2 years -20℃ Powder
1 week -4℃ in DMSO
1 month -80℃ in DMSO
Stability:
2 years -20℃ Powder
1 week -4℃ in DMSO
1 month -80℃ in DMSO
CAS No.155141-29-0
Biological ActivityRosiglitazone maleate (Avandia) is an anti-diabetic agent in the thiazolidinedione class of agents. Rosiglitazone maleate (Avandia) acts primarily by increasing insulin sensitivity. Rosiglitazone maleate (Avandia) improves glycemic control while reducing circulating insulin levels. Rosiglitazone is a member of the thiazolidinedione class of agents. They reduce glucose, fatty acid, and insulin blood concentrations. They work by binding to the peroxisome proliferator-activated receptors (PPARs). Thiazolidinediones enter the cell, bind to the nuclear receptors, and affect the expression of DNA. Rosiglitazone maleate (Avandia) also appears to have an anti-inflammatory effect in addition to its effect on insulin resistance.
M.W.473.5
ReferencesThe pharmacological and toxicological properties of this product have not been fully investigated. Exercise caution in use and handling. This product must not be used in humans.
Price211.2$
Research AreaStem Cells Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction
maleate (Avandia) is an anti-diabetic agent in the thiazolidinedione class of maleate (Avandia) acts primarily by increasing insulin sensitivity. Rosiglitazone improves glycemic control while reducing circulating insulin levels. Rosiglitazone is a thiazolidinedione class of agents. They reduce glucose, fatty acid, and insulin blood concentrations. by binding to the peroxisome proliferator-activated receptors (PPARs). Thiazolidinediones cell, bind to the nuclear receptors, and affect the expression of DNA. Rosiglitazone
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