(Sophoretin) is a PI3K and PKC inhibitor with IC50 of 3.8 μM and 15µg/ml. and Src kinases, mildly inhibited Akt1/2, and slightly affected PKC, p38 a naturally-occurring polar auxin transport inhibitor with IC50 of 0.8, of LDH% release, the inhibition of TNF-induced PMN-EC adhesion, synthesis and proliferation. It is a type of plant-based chemical, or and a plant-derived flavonoid found in fruits, vegetables, leaves and
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