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Nrf1 (9E6) Mouse mAb
Datasheet   

  • Catalog Number:

    E2200789

  • Amount:

    100ul

  • Source:

    Mouse

  • Form of Antibody:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

  • Specificity/Sensitivity:

    This antibody detects endogenous levels of NRF1,and does not cross-react with related proteins.

  • Entrez summary:

    This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration,heme biosynthesis,and mitochondrial DNA transcription and replication.The protein has also been associated with the regulation of neurite outgrowth.Alternate transcriptional splice variants,which encode the same protein, have been characterized.Additional variants encoding different protein isoforms have been described but they have not been fully characterized.Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for ""nuclear factor(erythroid-derived 2)-like 1"" which has an official symbol of NFE2L1.

  • UniPort summary Function:

    Transcription factor that activates the expression of the EIF2S1(EIF2-alpha)gene.Links the transcriptional modulation of key metabolic genes to cellular growth and development.Implicated in the control of nuclear genes required for respiration,heme biosynthesis,and mitochondrial DNA transcription and replication.

  • Immunogen:

    Purified recombinant human NRF1 protein fragments expressed in E.coli

  • Antibody type:

    Monoclonal Antibody

  • Isotype:

    IgG2a

  • Purification:

    Affinity Purified

  • Cellular localization:

    Nucleus

  • Reactivity:

    Human

  • Applications:

    WB

  • Molecular Weight:

    Calculated MW: 54 kDa; Observed MW: 72 kDa

  • UniProt Number:

    Q16656

  • Gene ID:

    4899

  • Gene symbol:

    ALPHA-PAL

  • Altername:

    alpha pal; alpha palindromic binding protein; Alpha palindromic-binding protein; Alpha-pal; locus control region factor 1; NFE2 related factor 1; NRF-1; Nrf1; NRF1_HUMAN; Nuclear respiratory factor 1; transcription factor 11.

  • Western blot analysis of NRF1 in Hela, K562, CEM and U2OS lysates using TCF11/NRF1 antibody.

  • Price:

    255$

  • Research Area:

    Autophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells

  • Product Type:

    Primary Antibody

  • Background:

    Transcription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene. Links the transcriptional modulation of key metabolic genes to cellular growth and development. Implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication.

  • Clone Number:

    9E6-H8-B6

  • Gene Name:

    NRF1

  • Recommended Dilutions:

    WB: 1/500-1/1000

  • Swiss-Prot No.:

    Q16656

  • Storage/Stability:

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

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Catalog Number

  • Amount:100ul
  • Price:255$

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Nrf1 (9E6) Mouse mAb | EnoGene Biotech Co. Ltd