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CKMT2 (3F4) Mouse mAb
Datasheet
Catalog Number:
E2200736Amount:
100ulSource:
MouseForm of Antibody:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.Specificity/Sensitivity:
This antibody detects endogenous levels of CKMT2 and does not cross-react with related proteins.Entrez summary:
Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gene.UniPort summary Function:
Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.Immunogen:
Purified recombinant human CKMT2 protein fragments expressed in E.coli.Antibody type:
Monoclonal AntibodyIsotype:
IgG2bPurification:
Affinity PurifiedCellular localization:
Cytoplasm, Cell membraneReactivity:
RatApplications:
WBMolecular Weight:
Calculated MW: 48 kDa; Observed MW: 48 kDaUniProt Number:
P17540Gene ID:
1160Gene symbol:
SMTCKAltername:
SMTCK
- Western blot analysis of CKMT2 in rat Brain lysates using CKMT2 antibody.
Price:
255$Research Area:
Autophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem CellsProduct Type:
Primary AntibodyBackground:
Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80% homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gene.Clone Number:
3F4-G5-H5Gene Name:
CKMT2Recommended Dilutions:
WB: 1/500-1/1000Swiss-Prot No.:
P17540Storage/Stability:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Catalog Number
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