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Beclin 1 (4F4) Mouse mAb
Datasheet   

  • Catalog Number:

    E2200675

  • Amount:

    100ul

  • Source:

    Mouse

  • Form of Antibody:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

  • Specificity/Sensitivity:

    This antibody detects endogenous levels of BECN1 and does not cross-react with related proteins.

  • Entrez summary:

    Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration (Zhong et al., 2009 [PubMed 19270693]).

  • UniPort summary Function:

    Plays a central role in autophagy. Required for the abcission step in cytokinesis. May play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus.

  • Immunogen:

    Purified recombinant human Beclin 1 protein fragments expressed in E.coli.

  • Antibody type:

    Monoclonal Antibody

  • Isotype:

    IgG1

  • Purification:

    Affinity Purified

  • Cellular localization:

    Golgi apparatus ? trans-Golgi network membrane; Peripheral membrane protein

  • Reactivity:

    Human,Mouse,Rat,Monkey,Hamster

  • Applications:

    WB

  • Molecular Weight:

    Calculated MW: 52 kDa; Observed MW: 55 kDa

  • UniProt Number:

    Q14457

  • Gene ID:

    8678

  • Gene symbol:

    ATG6; VPS30; beclin1

  • Altername:

    BECN1

  • Western blot analysis of Beclin 1 in Hela, 3T3, C6, COS7, CHO-K1, rat brain and Jurkat lysates using Beclin 1 antibody.

  • Price:

    255$

  • Research Area:

    Autophagy antibody

  • Product Type:

    Primary Antibody

  • Background:

    Plays a central role in autophagy. Required for the abcission step in cytokinesis. May play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus.

  • Clone Number:

    4F4-B10-C9

  • Gene Name:

    BECN1

  • Recommended Dilutions:

    WB: 1/500-1/1000

  • Swiss-Prot No.:

    Q14457

  • Storage/Stability:

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

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Catalog Number

  • Amount:100ul
  • Price:255$

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