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ATIC (3H12) Mouse mAb
Datasheet
Catalog Number:
E2200668Amount:
100ulSource:
MouseForm of Antibody:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.Specificity/Sensitivity:
This antibody detects endogenous levels of ATIC and does not cross-react with related proteins.Entrez summary:
This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria.UniPort summary Function:
Bifunctional enzyme that catalyzes 2 steps in purine biosynthesis.Immunogen:
Purified recombinant human ATIC protein fragments expressed in E.coli.Antibody type:
Monoclonal AntibodyIsotype:
IgG1Purification:
Affinity PurifiedCellular localization:
nullReactivity:
Human,Mouse,RatApplications:
WBMolecular Weight:
Calculated MW: 65 kDa; Observed MW: 65 kDaUniProt Number:
P31939Gene ID:
471Gene symbol:
PURH; AICAR; AICARFT; IMPCHASEAltername:
PURH; AICAR; AICARFT; IMPCHASE
- Western blot analysis of ATIC in various and lysates using ATIC antibody.
Price:
255$Research Area:
Autophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem CellsProduct Type:
Primary AntibodyBackground:
Bifunctional enzyme that catalyzes 2 steps in purine biosynthesis.Clone Number:
3H12-C9-H9Gene Name:
ATICRecommended Dilutions:
WB: 1/500-1/1000Swiss-Prot No.:
P31939Storage/Stability:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Catalog Number
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