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CHRDL1 Antibody
Datasheet
Catalog Number:
E2200591Amount:
100ulSource:
MouseForm of Antibody:
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerolSpecificity/Sensitivity:
This antibody detects endogenous levels of CHRDL1 and does not cross-react with related proteins.Entrez summary:
This gene encodes an antagonist of bone morphogenetic protein 4. The encoded protein may play a role in topographic retinotectal projection and in the regulation of retinal angiogenesis in response to hypoxia. Alternatively spliced transcript variants encoding different isoforms have been described.UniPort summary Function:
Antagonizes the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain by preventing the adoption of a glial fate. May play a crucial role in dorsoventral axis formation. May play a role in embyonic bone formation By similarity. May also play an important role in regulating retinal angiogenesis trough modulation of BMP4 actions in endothelial cells.Immunogen:
Purified recombinant human CHRDL1 protein fragments expressed in E.coli.Antibody type:
Monoclonal antibodyIsotype:
IgG1Purification:
Affinity purifiedCellular localization:
SecretedReactivity:
MApplications:
WB,ICCMolecular Weight:
57kDaUniProt Number:
Q9BU40Gene ID:
NM_145234.3Gene symbol:
CHL; VOPT; NRLN1; dA141H5.1Altername:
Neuralin-1 Neurogenesin-1 Ventroptin
- Immunocytochemistry stain of Hela using CHRDL1 antibody (1:300).
- Western blot detection of CHRDL1 in Rat kidney tissue lysates using CHRDL1 antibody (1:1000 diluted). Predicted band size: 57kDa Observed band size: 57kDa.
Price:
255$Research Area:
Autophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem CellsStorage/Stability:
Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
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