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Hexokinase II (1E8) Mouse mAb
Datasheet
Catalog Number:
E2200569Amount:
100ulSource:
MouseForm of Antibody:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.Specificity/Sensitivity:
This antibody detects endogenous levels Hexokinase-2( N-terminus) and does not cross-react with related proteins.Entrez summary:
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells. [provided by RefSeq, Apr 2009]UniPort summary Function:
nullImmunogen:
Recombinant human Hexokinase II protein.Antibody type:
Monoclonal AntibodyIsotype:
IgG1Purification:
Affinity PurifiedCellular localization:
Mitochondrion outer membrane.Reactivity:
Rat,Mouse,MonkeyApplications:
WBMolecular Weight:
Calculated MW: 102 kDa; Observed MW: 102 kDaUniProt Number:
P52789Gene ID:
3099Gene symbol:
HKII; HXK2Altername:
HKII; HXK2
- Western blot analysis of Hexokinase II in 3tT3, COS7 and C6 lysates using Hexokinase II
antibody. Price:
255$Research Area:
Autophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem CellsProduct Type:
Primary AntibodyBackground:
MiscellaneousIn vertebrates there are four major glucose-phosphorylating isoenzymes, designated hexokinase I, II, III and IV (glucokinase).Clone Number:
1E8-H3-F11Gene Name:
HK2Recommended Dilutions:
WB: 1/500-1/1000Swiss-Prot No.:
P52789Storage/Stability:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Flow Cytometry analysis of K562 cells stained with Hexokinase-2(N-terminus) (red, 1/100 dilution), followed by FITC-conjugated goat anti-mouse IgG. Blue line histogram represents the isotype control, normal mouse IgG.
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