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AMACR (2F3) Mouse mAb
Datasheet
Catalog Number:
E2200537Amount:
100ulSource:
MouseForm of Antibody:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.Specificity/Sensitivity:
This antibody detects endogenous levels AMACR(C-terminus) and does not cross-react with related proteins.Entrez summary:
This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)-and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described.UniPort summary Function:
Racemization of 2-methyl-branched fatty acid CoA esters. Responsible for the conversion of pristanoyl-CoA and C27-bile acyl-CoAs to their (S)-stereoisomersImmunogen:
Purified recombinant human AMACR(C-terminus) protein fragments expressed in E.coli.Antibody type:
Monoclonal AntibodyIsotype:
IgG1Purification:
Affinity PurifiedCellular localization:
Peroxisome. Mitochondrion.Reactivity:
Rat,HumanApplications:
WB,ICC/IFMolecular Weight:
Calculated MW: 42 kDa; Observed MW: 42 kDaUniProt Number:
Q9UHK6Gene ID:
23600Gene symbol:
RM; RACE; CBAS4; AMACRDAltername:
RM; RACE; CBAS4; AMACRD
- Western blot analysis of AMACR(Cterminus) in rat Liver lysates using AMACR(Cterminus)
antibody. 
- Immunocytochemistry analysis of AMACR (2F3) in Jurkat using AMACR (Cterminus)
antibody. Price:
255$Research Area:
Autophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem CellsProduct Type:
Primary AntibodyBackground:
Racemization of 2-methyl-branched fatty acid CoA esters. Responsible for the conversion of pristanoyl-CoA and C27-bile acyl-CoAs to their (S)-stereoisomers.Clone Number:
2F3-C11-B12Gene Name:
AMACRRecommended Dilutions:
WB: 1/500-1/1000 IF: 1/50-1/200Swiss-Prot No.:
Q9UHK6Storage/Stability:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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