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HK1(Hexokinase-1) Antibody
Datasheet
Catalog Number:
E2200515Amount:
100ulSource:
MouseForm of Antibody:
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerolSpecificity/Sensitivity:
This antibody detects endogenous levels of HK1 and does not cross-react with related proteins.Entrez summary:
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus; the remainder of the protein is identical among all the isoforms. A sixth transcript variant has been described, but due to the presence of several stop codons, it is not thought to encode a protein. [provided by RefSeq, Apr 2009]UniPort summary Function:
nullImmunogen:
Purified recombinant human HK1 protein fragments expressed in E.coli.Antibody type:
Monoclonal antibodyIsotype:
IgG1Purification:
Affinity purifiedCellular localization:
Mitochondrion outer membrane.Reactivity:
HApplications:
WB,ICCMolecular Weight:
102kDaUniProt Number:
P19367Gene ID:
NM_000188Gene symbol:
HKI; HXK1; HK1-ta; HK1-tb; HK1-tcAltername:
HK I,glycolytic enzyme,hexokinase type I brain form hexokinase
- Immunocytochemistry stain of Hela using HK1 antibody (1:300).
- Western blot detection of HK1 in Hela&Jurkat cell lysates using HK1 antibody (1:10000 diluted). Predicted band size: 102kDa Observed band size: 102kDa
Price:
255$Research Area:
Autophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem CellsStorage/Stability:
Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
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Catalog Number
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