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KRT18 (Keratin 18)Antibody
Datasheet
Catalog Number:
E2200493Amount:
100ulSource:
MouseForm of Antibody:
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerolSpecificity/Sensitivity:
This antibody detects endogenous levels of krt18 and does not cross-react with related proteins.Entrez summary:
KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.UniPort summary Function:
Involved in the uptake of thrombin-antithrombin complexes by hepatic cells By similarity. When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.Immunogen:
Purified recombinant human KRT18 protein fragments expressed in E.coli.Antibody type:
Monoclonal antibodyIsotype:
IgG2bPurification:
Affinity purifiedCellular localization:
Cytoplasm ? perinuclear regionReactivity:
HApplications:
WB,ICCMolecular Weight:
48kDaUniProt Number:
P05783Gene ID:
x12881Gene symbol:
K18; CYK18Altername:
Cell proliferation-inducing gene 46 protein;Cytokeratin-18;Keratin-18
- Immunocytochemistry stain of Hela using krt18 antibody (1:300).
- Western blot detection of KRT18 in Hela&MCF7 cell lysates and using KRT18 antibody (1:1000 diluted). Predicted band size: 48KDa Observed band size: 48KDa
Price:
255$Research Area:
Autophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem CellsStorage/Stability:
Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
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