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Intergrin alpha 5 Antibody
Datasheet
Catalog Number:
E2200486Amount:
100ulSource:
MouseForm of Antibody:
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerolSpecificity/Sensitivity:
This antibody detects endogenous levels Intergrin alpha 5(N-terminus) and does not cross-react with related proteins.Entrez summary:
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.UniPort summary Function:
Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi´s sarcoma lesionsImmunogen:
Purified recombinant human Intergrin alpha 5(N-terminus) protein fragments expressed in E.coli.Antibody type:
Monoclonal antibodyIsotype:
IgG2aPurification:
Affinity purifiedCellular localization:
Membrane; Single-pass type I membrane proteinReactivity:
HApplications:
WB,FCMolecular Weight:
145kDaUniProt Number:
P08648Gene ID:
NM_002205Gene symbol:
FNRA; CD49e; VLA5AAltername:
FNRA; CD49e; VLA5A
- Western blot detection of Intergrin alpha 5(N-terminus) antibody in Hela&HUVEC cell lysates using Intergrin alpha 5(N-terminus) antibody (1:1000 diluted). Predicted band size:145KDa Observed band size:145KDa.
- Flow Cytometry analysis of HeLa cells stained with Intergrin alpha 5(N-terminus) (red, 1/100 dilution), followed by FITC-conjugated goat anti-mouse IgG. Black line histogram represents the isotype control, normal mouse IgG.
Price:
255$Research Area:
Autophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem CellsStorage/Stability:
Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
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Catalog Number
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