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CYP7A1-C Antibody
Datasheet
Catalog Number:
E2200348Amount:
100ulSource:
MouseForm of Antibody:
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerolSpecificity/Sensitivity:
This antibody detects endogenous levels of CYP7A1(C-term) and does not cross-react with related proteins.Entrez summary:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway in the liver, which converts cholesterol to bile acids. This reaction is the rate limiting step and the major site of regulation of bile acid synthesis, which is the primary mechanism for the removal of cholesterol from the body.UniPort summary Function:
Catalyzes a rate-limiting step in cholesterol catabolism and bile acid biosynthesis by introducing a hydrophilic moiety at position 7 of cholesterol. Important for cholesterol homeostasis.Immunogen:
Purified recombinant human CYP7A1(C-term) protein fragments expressed in E.coli.Antibody type:
Monoclonal antibodyIsotype:
IgG1Purification:
Affinity purifiedCellular localization:
Endoplasmic reticulum membrane; Peripheral membrane protein..Reactivity:
H,M,RApplications:
WBMolecular Weight:
72kDaUniProt Number:
P22680Gene ID:
NM_000780Gene symbol:
CP7A; CYP7; CYPVIIAltername:
CP7A; CYP7; CYPVII; MGC126826; MGC138389
- Western blot detection of CYP7A1 in U251 MG,mouse pancreas,Rat testis, HepG2 & Hela cell lysates and using CYP7A1 antibody (1:1000 diluted). Predicted band size: 58KDa Observed band size:72KDa.
- Western blot detection of CYP7A1(C-terminus) antibody in HepG2 cell lysates using CYP7A1(C-terminus) antibody (1:1000 diluted). Predicted band size: 58KDa Observed band size: 72KDa.
Price:
255$Research Area:
Autophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem CellsStorage/Stability:
Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
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Catalog Number
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