TBL1XR1 (4F3) Mouse mAb
Datasheet   

  • Catalog Number:

    E2200319
  • Amount:

    100ul
  • Source:

    Mouse
  • Form of Antibody:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
  • Specificity/Sensitivity:

    This antibody detects endogenous levels TBLR1 and does not cross-react with related proteins.
  • Entrez summary:

    TBLR1 is an F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. It plays an essential role in transcription activation mediated by nuclear receptors and probably acts as an integral component of the N-Cor corepressor complex that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteosomal degradation of the N-Cor complex, thereby allowing cofactor exchange, and transcription activation.
  • UniPort summary Function:

    F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of the N-Cor corepressor complex that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of N-Cor complex, th ereby allowing cofactor exchange, and transcription activation.
  • Immunogen:

    Purified recombinant human TBLR1 protein fragments expressed in E.coli.
  • Antibody type:

    Monoclonal Antibody
  • Isotype:

    IgG1
  • Purification:

    Affinity Purified
  • Cellular localization:

    Nucleus
  • Reactivity:

    Human,Mouse
  • Applications:

    WB,IHC-F,IHC-P,ICC/IF
  • Molecular Weight:

    Calculated MW: 56 kDa; Observed MW: 60 kDa
  • UniProt Number:

    Q9BZK7
  • Gene ID:

    79718
  • Gene symbol:

    C21; DC42; IRA1; TBLR1
  • Altername:

    C21; DC42; F box like/WD repeat containing protein TBL1XR1; F-box-like/WD repeat-containing protein TBL1XR1; FLJ12894; IRA1; Nuclear receptor corepressor/HDAC3 complex subunit; Nuclear receptor corepressor/HDAC3 complex subunit TBLR1; TBL1 related protein 1; TBL1-related protein 1; TBL1R_HUMAN; TBL1XR1; Transducin (beta) like 1 X linked receptor 1; Transducin beta like 1X related protein 1; Transducin beta-like 1X-related protein 1.
  • Western blot analysis of Phospho-p27 KIP 1 (Ser10) in Hela, 3T3 lysates using Phospho-p27 Kip 1 (Ser10) antibody.
  • Immunohistochemistry analysis of paraffin-embedded Human breast cancer using p27 KIP 1 (Phospho-Ser10) antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
  • Price:

    255$
  • Research Area:

    Autophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells
  • Product Type:

    Primary Antibody
  • Background:

    F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors.
  • Clone Number:

    4F3-A8-D9
  • Gene Name:

    TBL1XR1
  • Recommended Dilutions:

    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
  • Swiss-Prot No.:

    Q9BZK7
  • Storage/Stability:

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • paraffin-embedded huma breast cancer using anti- TBLR1 diluted 1/500-1/1000.

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Catalog Number

  • Amount:100ul
  • Price:255$

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AbPromise
TBL1XR1 (4F3) Mouse mAb | EnoGene Biotech Co. Ltd