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Cytokeratin 7 (4G9) Mouse mAb
Datasheet   

  • Catalog Number:

    E2200296

  • Amount:

    100ul

  • Source:

    Mouse

  • Form of Antibody:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

  • Specificity/Sensitivity:

    This antibody detects endogenous levels Keratin 7 and does not cross-react with related proteins.

  • Entrez summary:

    he protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia ining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described.

  • UniPort summary Function:

    Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7).

  • Immunogen:

    Purified recombinant human Keratin 7 protein fragments expressed in E.coli.

  • Antibody type:

    Monoclonal Antibody

  • Isotype:

    IgG2b

  • Purification:

    Affinity Purified

  • Cellular localization:

    Cytoplasm

  • Reactivity:

    Human

  • Applications:

    WB,ICC/IF

  • Molecular Weight:

    Calculated MW: 51 kDa; Observed MW: 55 kDa

  • UniProt Number:

    P08729

  • Gene ID:

    3855

  • Gene symbol:

    K7; CK7; SCL; K2C7

  • Altername:

    CK 7; CK-7; ck7; Cytokeratin 7; Cytokeratin-7; Cytokeratin7; D15Wsu77e; K2C7; K2C7_HUMAN; K7; Keratin 55k type ii cytoskeletal; Keratin 7; Keratin simple epithelial type 1 k7; Keratin type II cytoskeletal 7

  • Western blot analysis of Keratin 7(Cterminus) in T47D, Hela and HepG2 lysates using Keratin 7(Cterminus) antibody.

  • Immunocytochemistry analysis of Cytokeratin 7 in HeLa cells using Cytokeratin 7 antibody.

  • Price:

    255$

  • Research Area:

    Autophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells

  • Product Type:

    Primary Antibody

  • Background:

    K7 a type II cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Phosphorylation of keratins at specific sites affects their organization, assembly dynamics, and their interaction with signaling molecules. Specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels.

  • Clone Number:

    4G9-D8-H6

  • Gene Name:

    KRT7

  • Recommended Dilutions:

    WB: 1/500-1/1000 IF: 1/50-1/200

  • Swiss-Prot No.:

    P08729

  • Storage/Stability:

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

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Catalog Number

  • Amount:100ul
  • Price:255$

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Cytokeratin 7 (4G9) Mouse mAb | EnoGene Biotech Co. Ltd