COX IV (4D11) Mouse mAb
Datasheet   COA   

  • Catalog Number:

    E2200147
  • Amount:

    100ul
  • Source:

    Mouse
  • Form of Antibody:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
  • Specificity/Sensitivity:

    This antibody detects endogenous levels of COX4(C-terminus) and does not cross-react with related proteins
  • Entrez summary:

    Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes isoform 2 of subunit IV. Isoform 1 of subunit IV is encoded by a different gene, however, the two genes show a similar structural organization. Subunit IV is the largest nuclear encoded subunit which plays a pivotal role in COX regulation.
  • UniPort summary Function:

    This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport
  • Immunogen:

    A synthetic peptide corresponding to carboxyl terminal residues of human COX IV
  • Antibody type:

    Monoclonal Antibody
  • Isotype:

    IgG1
  • Purification:

    Affinity Purified
  • Cellular localization:

    Mitochondrion inner membrane
  • Reactivity:

    Human,Mouse,Rat,Hamster,Goat,Monkey
  • Applications:

    WB,IHC-F,IHC-P,ICC/IF,IP,FC
  • Molecular Weight:

    Calculated MW: 20 kDa; Observed MW: 17 kDa
  • UniProt Number:

    P13073
  • Gene ID:

    1327
  • Gene symbol:

    COX4I2; COX4B; COX4-2; COX4L2; COXIV-2; dJ857M17.2
  • Altername:

    COX 4; Cox4a; COX4B; COXIV; Cytochrome c oxidase subunit 4 isoform 1 mitochondrial; MGC105470; dj857M17.2; Cytochrome
  • Western blot analysis of COX IV in mouse skeletal muscel and Jurkat lysates using COX IV antibody.
  • Price:

    255$
  • Research Area:

    Autophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells
  • Product Type:

    Loading Control Antibody
  • Background:

    This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
  • Clone Number:

    4D11-B3-E8
  • Gene Name:

    COX4I1
  • Recommended Dilutions:

    WB: 1/1000 IHC: 1/50-1/200 IF: 1/100-1/200 IP: 1/20 FC: 1/100
  • Swiss-Prot No.:

    P13073
  • Storage/Stability:

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Western blot detection of COX4(C-terminus) antibody in Mouse skeletal muscel&Jurkat lysates using COX4(C-terminus) antibody (1:1000 diluted). Predicted size: 20KDa Observed band size: 20KDa.
  • analysis of K562 cells stained with COX4 (red, 1/100 dilution), followed by Blue line histogram represents the isotype control, normal mouse IgG.

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Catalog Number

  • Amount:100ul
  • Price:255$

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AbPromise
COX IV (4D11) Mouse mAb | EnoGene Biotech Co. Ltd