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USP7 Antibody
Datasheet
Catalog Number:
E220014-1Amount:
50ulBackground:
Mouse monoclonal IgG to USP7Gene ID:
NM_003470.2Immunogen:
Recombinant fragment of Human USP7 (N-terminus).Reactivity:
Hu
Tested applicationsRecommended Dilutions:
. ELISA: 1/5000 - 1/20000. WB: 1/100-1/2000.Cellular localization:
NucleusRelevance:
USP7 strongly stabilizes p53 even in the presence of excess MDM2, and induces p53-dependent cell growth repression and apoptosis. USP7 has an intrinsic enzymatic activity that specifically de-ubiquitinates p53 both in vivo and in vitro. This protein may function as a tumor suppressor in vivo through the stabilization of p53. It is also known that USP7 interacts with herpesvirus 1 trans-acting transcriptional protein ICP0/VMW110 and Epstein-Barr virus EBNA1.Purity:
Protein G-Sepharose affinity purifiedForm of Antibody:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.Preservative:
0.02% Sodium Azide and 50% glycerol, 1%BSA, PBS, pH7.4.Storage/Stability:
Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
- USP7 antibody (E220014) at 1/500 dilution. Hela whole cell lysate 40ug/Lane. Predicted band size: 130Kda. Observed band size: 130Kda.
Price:
145$Research Area:
Autophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem CellsPurification:
Affinity purified
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Catalog Number
- Amount:50ul
- Price:145$
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