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SMYD2 Antibody
Datasheet   

  • Catalog Number:

    E2200130

  • Amount:

    100ul

  • Source:

    Mouse

  • Form of Antibody:

    Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol

  • Specificity/Sensitivity:

    This antibody detects endogenous levels of SMYD2 and does not cross-react with related proteins.

  • Entrez summary:

    SET domain-containing proteins, such as SMYD2, catalyze lysine methylation (Brown et al., 2006 [PubMed 16805913]).[supplied by OMIM, Nov 2008]

  • UniPort summary Function:

    Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins. Specifically methylates histone H3 ´Lys-4´ (H3K4me) and dimethylates histone H3 ´Lys-36´ (H3K36me2). Has also methyltransferase activity toward non-histone proteins such as p53/TP53 and RB1. Monomethylates ´Lys-370´ of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates ´Lys-860´ of RB1/RB.

  • Immunogen:

    Purified recombinant human SMYD2 protein fragments expressed in E.coli.

  • Antibody type:

    Monoclonal antibody

  • Isotype:

    IgG2b

  • Purification:

    Affinity purified

  • Cellular localization:

    Cytoplasm ? cytosol；Nucleus

  • Reactivity:

    H,M

  • Applications:

    WB

  • Molecular Weight:

    50kDa

  • UniProt Number:

    Q9NRG4

  • Gene ID:

    NM_020197

  • Gene symbol:

    KMT3C; HSKM-B; ZMYND14

  • Altername:

    HSKM-B；Histone methyltransferase SMYD2，EC=2.1.1.43；Lysine N-methyltransferase 3C；SET and MYND domain-containing protein 2

  • Western blot detection of SMYD2 in 3T3,HT1080，A431&Jurkat cell lysates and using SMYD2 antibody (1:1000 diluted). Predicted band size: 50KDa Observed band size: 50KDa

  • Price:

    255$

  • Research Area:

    Autophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells

  • Storage/Stability:

    Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

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Catalog Number

  • Amount:100ul
  • Price:255$

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SMYD2 Antibody | EnoGene Biotech Co. Ltd