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Cytokeratin 18 Mouse Monoclonal Antibody (8F2)
Datasheet
Catalog Number:
E12-124Amount:
100μg/100μlClone Number:
8F2Background:
Keratin 18 is a type I cytokeratin. It is, together with its filament partner keratin 8, perhaps the most commonly found products of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.Keratin 18 is often used together with keratin 8 and keratin 19 to differentiate cells of epithelial origin from hematopoietic cells in tests that enumerate circulating tumor cells in blood.Form of Antibody:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Storage/Stability:
Store at -20℃/1 yearSpecificity/Sensitivity:
Antibody can detects endogenous Cytokeratin 18 protein.Reactivity:
H, R, MApplications:
WB: 1:1,000-3,000
- Western blot analysis of 1) HepG2, 2) Hela, 3) Mouse Liver tissue, 4) C2C12, 5) Rat Heart tissue, 6) Mouse Skeletal Muscle tissue with Cytokeratin 18 Mouse MAb (8F2) diluted at 1:2000.
Price:
225$
Immunohistochemical analysis of paraffin-embedded human breast caricnoma using Cytokeratin 18 Mouse mAb diluted at 1:500.
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