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CK16 Mouse Monoclonal Antibody
Datasheet
Catalog Number:
E12-079Amount:
100μg/100μlClone Number:
6F6Background:
Keratin 16 is expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation-related keratins). Keratin 16 is absent in normal breast tissue and in noninvasive breast carcinomas. Only 10% of the invasive breast carcinomas show diffuse or focal positivity. Reportedly, a relatively high concordance was found between the carcinomas immunostaining with the basal cell and the hyperproliferation-related keratins, but not between these markers and the proliferation marker Ki-67. This supports the conclusion that basal cells in breast cancer may show extensive proliferation, and that absence of Ki-67 staining does not mean that (tumor) cells are not proliferating.Form of Antibody:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Storage/Stability:
Store at -20℃/1 yearSpecificity/Sensitivity:
The CK16 Mouse Monoclonal antibody detects endogenous CK16 proteins. (~51KD ).Reactivity:
Human, Mouse, RatApplications:
IHC: 1:200
- IHC staining of human gullet cancer tissue with CK16 mouse mAb(6F6) diluted at 1:200.
Price:
255$
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Catalog Number
- Amount:100μg/100μl
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