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EGFR Mouse Monoclonal Antibody
Datasheet
Catalog Number:
E12-064Amount:
100μg/100μlClone Number:
1B1Background:
The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades.Form of Antibody:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Storage/Stability:
Store at -20℃/1 yearSpecificity/Sensitivity:
The EGFR Mouse Monoclonal antibody detects endogenous EGFR proteins (170KD).Reactivity:
HumanApplications:
WB: 1:1,000
- Western blot analysis of Hela cell lysate with EGFR mAb diluted at 1:1,000.
Price:
255$
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Catalog Number
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