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PEK/PERK (Phospho-Thr981) Antibody
Datasheet   

  • Catalog Number:

    E11-8168A

  • Amount:

    100μg

  • Swiss-Prot No.:

    Q9NZJ5

  • Other Names:

    E2AK3; EC 2.7.11.1; EIF2AK3; Eukaryotic translation initiation factor 2-alpha kinase 3 precursor; HsPEK; kinase PERK; Pancreatic eIF2-alpha kinase; PEK; PERK; PRKR-like endoplasmic reticulum kinase

  • All Sites:

    Human: Thr981; Mouse: Thr980; Rat: Thr974

  • Storage/Stability:

    Store at -20℃/1 year

  • Form of Antibody:

    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

  • Immunogen:

    The antiserum was produced against synthesized phosphopeptide derived from human PEK/PERK around the phosphorylation site of threonine 981 (R-H-TP-G-Q).

  • Purification:

    The antibody was affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

  • Specificity/Sensitivity:

    PEK/PERK (Phospho-Thr981) antibody detects endogenous levels of PEK/PERK only when phosphorylated at threonine 981.

  • Reactivity:

    Human (Identities = 100%, Positives = 100%); Mouse (Identities = 92%, Positives = 92%);Rat (Identities = 92%, Positives = 92%)

  • Applications:

    IHC: 1:50~1:100 ELISA: 1:40000

  • References:

    Shi Y., An J., J. Biol. Chem. 274:5723-5730(1999).
    Sood R., Biochem. J. 346:281-293(2000).
    The MGC Project Team; Genome Res. 14:2121-2127(2004).

  • P-peptide - +

  • Immunohistochemistry analysis of paraffin-embedded human prostate carcinoma tissue using PEK/PERK (Phospho-Thr981) antibody.
    PEK/PERK (Phospho-Thr981) antibody reacts with epitope-specific phosphopeptide and corresponding non-phosphopeptide. The absorbance readings at 450 nM are shown in the ELISA figure.

  • Price:

    225$

  • Research Area:

    Autophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells

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Catalog Number

  • Amount:100μg
  • Price:225$

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