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IR (Phospho-Thr1375) Antibody
Datasheet   

  • Catalog Number:

    E11-8116A

  • Amount:

    100μg

  • Swiss-Prot No.:

    P06213

  • Other Names:

    CD220 antigen; EC 2.7.10.1; insulin receptor; IR; kinase InsR

  • All Sites:

    Human: Thr1375; Mouse: Thr1365; Rat: Thr1376

  • Storage/Stability:

    Store at -20℃/1 year

  • Form of Antibody:

    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

  • Immunogen:

    The antiserum was produced against synthesized phosphopeptide derived from human INSR around the phosphorylation site of threonine 1375 (I-L-TP-L-P).

  • Purification:

    The antibody was affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

  • Specificity/Sensitivity:

    INSR (Phospho-Thr1375) antibody detects endogenous levels of INSR only when phosphorylated at threonine 1375.

  • Reactivity:

    Human (Identities = 100%, Positives = 100%); Mouse (Identities = 92%, Positives = 100%);Rat (Identities = 92%, Positives = 100%)

  • Applications:

    WB: 1:500~1:1000 ELISA: 1:5000

  • References:

    Ebina Y., Cell 40:747-758(1985).
    Ullrich A., Nature 313:756-761(1985).
    Seino S., Diabetes 39:123-128(1990).

  • Western blot analysis of extracts from HepG2 cells, using INSR (Phospho-Thr1375) antibody.

  • Price:

    225$

  • Research Area:

    Autophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells

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Catalog Number

  • Amount:100μg
  • Price:225$

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