All Names
AlternameInsulin receptor substrate 1,IRS1 CORONARY ARTERY DISEASE
Form Or Antibody
Form of AntibodyRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/StabilityStore at -20℃/1 year
ImmunogenThe antiserum was produced against synthesized non-phosphopeptide derived from human IRS-1 around the phosphorylation site of serine 307 (T-E-S-I-T).
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificty Sensitivity
Specificity/SensitivityIRS-1 (Ab-307) antibody detects endogenous levels of tota IRS-1 protein.
ReferencesPhilip J. Papst, et al. (1998) J. Biol. Chem; 273: 15077.
Satoru Eguchi, et al. (999) J. Biol. Chem 1; 274: 36843.
Ana González-García, et al. (2002) J. Biol. Chem; 277: 1500-1508.
Ulrike Krause, et al. (2002) Eur. J. Biochem; 269: 3751.