All Names
AlternameCD61 antigen, GP3A, GPIIIa, ITB3, Integrin beta-3 precursor, Platelet membrane glycoprotein IIIa, integrin beta-3
All SitesHuman: Thr785; Mouse: Thr784
Form Or Antibody
Form of AntibodyRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/StabilityStore at -20℃/1 year
ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human Integrin β3 around the phosphorylation site of tyrosine 785 (I-T-YP-R-G).
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/SensitivityIntegrin β3 (phospho-Tyr785) antibody detects endogenous levels of Integrin β3 only when phosphorylated at tyrosine 785.
ReferencesAnirban Datta, J. Biol. Chem., Feb 2002; 277: 3943 - 3949.
Alison L. Jenkins, J. Biol. Chem., May 1998; 273: 13878.
Scott D. Blystone, J. Biol. Chem., Nov 1997; 272: 28757.
Rita I. Kirk, J. Biol. Chem., Sep 2000; 275: 30901.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells