Other Names HD2; histone deacetylase 2; YY1 transcription factor binding protein; YY1BP
All Sites Human: Ser394; Mouse: Ser394
Storage/Stability Store at -20℃/1 year
Form Or Antibody
Form of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human HDAC2 around the phosphorylation site of serine 394 (E-D-SP-G-D).
Purification The antibody was affinity-purified fromrabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivity HDAC2 (Phospho-Ser394) antibody detects endogenous levels of HDAC2 only when phosphorylated at serine 394.
ReferencesYang W.-M., Proc. Natl. Acad. Sci. U.S.A. 93:12845-12850(1996).
Mungall A.J., Nature 425:805-811(2003).
Schmidt D.R., Biochemistry 38:14711-14717(1999).
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells