All Names
AlternameGLR1, GLUH1, GRIA1, GluR-1, GluR-A, GluR-K1, Glutamate receptor 1 precursor, Glutamate receptor ionotropic, AMPA 4
All SitesHuman: Ser849; Mouse: Ser849; Rat: Ser849
Form Or Antibody
Form of AntibodyRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/StabilityStore at -20℃/1 year
ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human GluR1 around the phosphorylation site of serine 849 (Q-Q-SP-I-N).
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/SensitivityGluR1 (phospho-Ser849) antibody detects endogenous levels of GluR1 only when phosphorylated at serine 849.
ReferencesDavide Ragozzino, J. Neurosci., Oct 2006; 26: 10488 - 10498.
Raymond Dingledine, Pharmacol. Rev., Mar 1999; 51: 7.
E Carafoli, Crit. Rev. Biochem. Mol. Biol., Apr 2001; 36: 107.
Jianqun Wu, J Neurophysiol, Jun 2006; 95: 3519 - 3527.