All Names
AlternameGAB1, GRB2-associated-binding protein 1
All SitesHuman: Tyr627; Mouse: Tyr628
Form Or Antibody
Form of AntibodyRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/StabilityStore at -20℃/1 year
ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human Gab1 around the phosphorylation site of tyrosine 627 (V-E-YP-L-D).
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/SensitivityGab1(phospho-Tyr627) antibody detects endogenous levels of Gab1 only when phosphorylated at tyrosine 627.
ReferencesAnders Kallin, et,al. (2004) J. Biol. Chem; 279: 17897-17904.
Hideto Kameda, et,al. (2001) Cell Growth Differ; 12: 307.
Masaki Osawa, et,al. (2002) J. Cell Biol; 158: 773.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells