All Names
AlternameDOK1 Docking protein 1
All SitesHuman: Tyr398; Mouse: Tyr397; Rat: Tyr472
Form Or Antibody
Form of AntibodyRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/StabilityStore at -20℃/1 year
ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human p62Dok around the phosphorylation site of tyrosine 398 (E-G-YP-E-L).
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/Sensitivityp62Dok (Phospho-Tyr398) antibody detects endogenous levels of p62Dok only when phosphorylated at tyrosine 398.
ReferencesMichael J. Wick, et,al. (2001) J. Biol. Chem; 276: 42843-42850.
Paul D. Simoncic, et,al. (2006) Mol. Cell. Biol; 26: 4149-4160.
Nadia Dubé, et,al. (2004) PNAS; 101: 1834.
Adam C. Yopp, et,al . (2005) J. Immunol; 175: 2913-2924.