All Names
AlternameCREB1, cAMP response element-binding protein
All SitesHuman: Ser129; Mouse: Ser129; Rat: Ser129
Form Or Antibody
Form of AntibodyRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/StabilityStore at -20℃/1 year
ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human CREB around the phosphorylation site of serine 129 (I-L-SP-R-R) (CKRREILSRRPSYR).
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/SensitivityCREB (phospho-Ser129) antibody detects endogenous levels of CREB only when phosphorylated at serine 129.
ReferencesChrystelle V. Garat, et al. (2006) Mol. Cell. Biol; 26: 4934-4948.
Lilah Rothem,et al. (2004) Mol. Pharmacol; 66: 1536-1543.
Darren R. Tyson, et,al. (2002) Endocrinology; 143: 674.
Kyung-Woo Park, et al. (2003)Arterioscler. Thromb. Vasc. Biol; 23: 1364.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells