All Names
AlternameAmplaxin, CTTN, EMS1, Oncogene EMS1, SRC8, Src substrate cortactin
Form Or Antibody
Form of AntibodyRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/StabilityStore at -20℃/1 year
ImmunogenThe antiserum was produced against synthesized non-phosphopeptide derived from human Cortactin around the phosphorylation site of tyrosine 421 (P-I-YP-E-D).
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificty Sensitivity
Specificity/SensitivityCortactin (Ab-421) antibody detects endogenous levels of total Cortactin protein.
ReferencesDu, Y. et al. (1998) Mol. Cell. Biol. 18, 5838-5851.
Naisbitt, S. et al. (1999) Neuron 23, 569-582.
Rodrigo, J. P. et al. (2000) Clin. Cancer Res. 6, 3177-3182.
Weed, S.A. and Parsons, J.T. (2001) Oncogene 20, 6418-6434.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells