All Names
AlternameBCR, BCR protein, BCR1, Breakpoint cluster region protein
All SitesHuman: Tyr177; Rat: Tyr72
Form Or Antibody
Form of AntibodyRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/StabilityStore at -20℃/1 year
ImmunogenThe antiserum was produced against synthesized phosphopeptide derived from human Bcr around the phosphorylation site of tyrosine177 (P-F-YP-V-N).
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Specificty Sensitivity
Specificity/SensitivityBcr (phospho-Tyr177) antibody detects endogenous levels of Bcr only when phosphorylated at tyrosine 177.
ReferencesML Campbell, Cell Growth Differ., Jul 1993; 4: 581.
Asok Mukhopadhyay, J. Biol. Chem., Aug 2002; 277: 30622 - 30628.
Jeanne Wilson-Rawls, Cancer Res., Aug 1996; 56: 3426 - 3430.
Lori Rink, Blood, Apr 2007; 10.1182.
Research AreaAutophagy antibody Cancer Cardiovascular Cell Biology Epigenetics & Nuclear Signaling Developmental Biologys Immunology Drug Discovery Products Metabolism Neuroscience Signal Transduction Stem Cells